Schedule 1 Complete Guide: Characters, Drug Crafting, Factions, Combat, and Endings

June 17, 2025

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Schedule 1 is a dark, strategy-driven survival game set in a dystopian world where drugs are both lifeline and leverage. You play as a rogue biochemist navigating dangerous factions, ethical dilemmas, and tactical challenges. With deep mechanics around chemistry, alliances, and base-building, mastering the game requires sharp planning and difficult choices. This guide covers all core systems, from crafting drugs to unlocking the best ending paths.

  1. Understanding the Core Gameplay

Schedule 1 combines survival sim elements with RPG dialogue, chemistry puzzles, and strategic combat.

  • The player crafts and distributes drugs.

  • Every decision affects reputation, morality, and story progression.

Key to survival is understanding how drug production connects with factions and narrative branches.

Read more: The Hidden Addiction: Deep Dive into Resource Scarcity in Schedule

  1. Choosing Your Starting Character

Players begin by selecting one of three character types:

  • The Chemist: Great at crafting, weak in combat.

  • The Enforcer: Strong in battle, poor at chemistry.

  • The Diplomat: Balanced, ideal for faction negotiations.

 

Beginners should choose The Diplomat for more flexible outcomes and dialogue options.

  1. Exploring the Early Game Map

The first zones include The Slums, Old Clinics, and Quarantine Corridor. These areas have limited supplies but are full of threats.

Tips:

  • Travel during daylight to avoid ambushes.

  • Use hiding spots near ruined pharmacies to stock up safely.

Upgrade your first safehouse early to access basic crafting tools and item storage.

  1. Crafting Drugs and Managing Chemistry

The central mechanic is synthesizing controlled substances using:

  • Temperature control

  • Reaction timing

  • Solvent mixing

Drug classes include:

  • Schedule A: Healing

  • Schedule B: Strength and reflex boosters

  • Schedule C: Mood and perception modifiers

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Each successful recipe unlocks reputation points and faction quests.

  1. Understanding Faction Relations

The world is divided into four factions:

  • The Syndicate: Militarized, dominant.

  • The Dawn Network: Tech-driven cult.

  • The Freemen: Resistance and grassroots medics.

  • The Vault: Elite pharma executives.

Actions that affect reputation:

  • Supplying drugs to different groups.

  • Killing or saving faction members.

  • Completing moral or immoral quests.

Aligning with a faction changes your storyline and available missions.

  1. Building and Upgrading Your Base

Your lab starts small but can become a self-sufficient compound.

Key upgrades:

  • Synthesizer bench

  • Auto-distiller

  • Defense turret and motion alarm

Mid-game, you’ll need to defend your base from raids and infiltrators, especially if your drug operation grows large.

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  1. Combat and Evasion Tactics

Combat is fast and punishing. Most fights are avoidable but sometimes necessary.

Weapon types:

  • Improvised melee tools

  • Syringe darts

  • Shock-field grenades

Tips:

  • Use drugs like Reflexin before fights for stat boosts.

  • Set traps around your lab before major missions.

 
  1. Moral Dilemmas and Branching Story Paths

Your decisions shape the world:

  • Help a sick child and lose ingredients, or sell them for faction favor?

  • Destroy or distribute a formula for a neurological weapon?

Every choice affects:

  • NPC trust

  • Access to rare formulas

  • World state (e.g. epidemic spread, riot levels)

  1. Unlocking Hidden Zones and Events

Beyond the map's surface are locked labs, ruins, and data vaults.

How to unlock them:

  • Gain maximum rep with The Vault to access restricted areas.

  • Find experimental formula logs to trigger hidden cutscenes.

Use perception-enhancing drugs to detect hidden doors and item caches.

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  1. Endings and How to Unlock Them

There are six total endings:

Main Endings:

  • Liberation: Cure the world, dismantle the system.

  • Domination: Become a new cartel leader.

  • Exodus: Escape with the cure, leaving others behind.

  • Collapse: Trigger faction war.

Secret Endings:

  • Redemption: Heal yourself and reform society.

  • Singularity: Merge with the synthetic drug network and ascend.

Tips:

  • Keep a high morality score to unlock Redemption.

  • Complete all “Key Data Logs” to trigger the Singularity path.

Schedule 1 is a tough but rewarding game that combines moral choices with deep systems. It asks players not only how to survive, but what survival should mean in a broken world. With the right builds, strategies, and alliances, you can steer the world toward redemption—or plunge it into deeper chaos.